CellGenix® rh IFN-γ

Preclinical grade

CellGenix Recombinant Human IFN-γ reliably promotes the maturation of monocyte-derived dendritic cells (Mo-DCs) and the generation of cytokine induced killer cells (CIK cells). It is produced in our dedicated animal-free facility ensuring maximum safety for optimal use in ATMP manufacturing.

General Information

Interferon-γ (IFN-γ) is a cytokine that is critical for innate and adaptive immunity against viral, some bacterial and protozoal infections. It is the only member of the type II class of interferons and is predominantly produced by natural killer cells (NK cells) and T cells.

IFN-γ is used in the cell and gene therapy space for the ex vivo maturation of Mo-DCs, ex vivo generation of CIK cells and stimulation of monocytes, macrophages and microglia.

Preclinical Grade

The final manufacturing steps and quality control of all our preclinical grade products are performed in a GMP facility ensuring a consistent high quality.

name
CellGenix® Recombinant Human Interferon-gamma
Source
E. coli
Formulation
Lyophilized
ANIMAL-DERIVED COMPONENT-FREE
CellGenix® Preclinical rh IFN-γ
amount
Order Number
50  µg
1425-050

CellGenix® rh IFN-γ

Features

  • Produced in our dedicated animal-free facility
  • High purity, activity and product stability

Applications

Technical Details

Source
Expressed in E. coli
Description

Human Interferon-gamma, accession # P01579, Gln24-Arg162

Formulation

Lyophilized from a 0.2 µm-filtered solution containing 20 mM succinate, pH 5.0

Final manufacturing steps and Quality Control (QC) are performed in a GMP facility.

 Preclinical
Molecular weight16.5 kDa
Purity≥ 95% as determined by SDS-PAGE
Activity≥ 10 x 106 IU/mg, calibrated against Imukin®
Endotoxin level< 1000 EU/mg
Intended useIntended for preclinical ex vivo use. Not intended for human in vivo application.

Handling Instructions

Reconstitution

Recommended in sterile water to a final concentration of 250 µg/ml.

Shipment

Ambient temperature. Please refer to Technote to learn more about our shipment validation procedure.

Expiry

3 years from date of shipment.

Storage & Stability

Store lyophilized cytokine at -20°C to -80°C.

Avoid repeated freeze/thaw cycles.

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